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New therapies for hepatocellular carcinoma

✍ Scribed by Avila, M A; Berasain, C; Sangro, B; Prieto, J

Book ID
110070569
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
378 KB
Volume
25
Category
Article
ISSN
0950-9232

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πŸ“œ SIMILAR VOLUMES

A new approach to therapy for hepatocell
A new approach to therapy for hepatocellular carcinoma?
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Objective: To assess the efficacy of 3-bromopyruvate (3-BrPA), a strong alkylating agent that inhibits hexokinase and mitochondrial oxidative phosphorylation, resulting in decreased cellular ATP production, on rabbit VX2 tumor cells. Methods: Adult New Zealand White rabbits were used for the study.

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The recurrence of hepatocellular carcinoma (HCC) is a major cause of mortality for patients transplanted with HCC. There currently exists no standard method for identifying those patients with a high risk for recurrence. Identification of factors leading to recurrence is necessary to develop an effi