New therapeutic strategies for the treatment of acute lymphoblastic leukaemia
β Scribed by Pui, Ching-Hon; Jeha, Sima
- Book ID
- 109950246
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 474 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1474-1776
- DOI
- 10.1038/nrd2240
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Serial liver function tests and percutaneous liver biopsies were performed on 21 children receiving treatment for acute lymphoblastic leukaemia (ALL). The patients received continuing chemotherapy either with daily 6-mercaptopurine and weekly methotrexate or with five-day pulses of these drugs every
## Abstract Ovarian function was assessed in 40 long term survivors who had received standard United Kingdom Acute Lymphoblastic Leukaemia (UKALL) protocols and were in first clinical and haematological remission. A menstrual and pregnancy history was taken (median age at assessment: 18.8 (12β34.7