✦ LIBER ✦

New technique of complete thymectomy in adult rats without tracheal intubation

✍ Scribed by Luc Delrivière; Paul Gibbs; Eiji Kobayashi; Naoshi Kamada; Pierre Gianello

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 84 KB
Volume: 18
Category: Article
ISSN: 0738-1085
DOI: 10.1002/(sici)1098-2752(1998)18:1<6::aid-micr2>3.0.co;2-m

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✦ Synopsis

Adult rat thymectomy is frequently performed as part of the protocol for experiments in transplant immunology. Current methods used are either imprecise (suction methods) or require tracheal intubation (surgical technique) and are thus difficult to master. We have developed a safe technique of surgical removal of the thymus with resolution of any pneumothorax by suction through the xyphoid insertions of the diaphragm. This method is easy to learn and gives a 95% success rate.