✦ LIBER ✦
New Synthons for the Synthesis of Lanthanide Containing Macrocyclic Schiff Bases Featuring Substituents Available for Tethering
✍ Scribed by Arnaud Dumont; Vincent Jacques; Jean F Desreux
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 188 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
AbstractÐ2,6-Diacetylpyridine substituted with amine or alcohol groups in the 4-position have been prepared from chelidamic acid. The key 4-chloro derivative was synthesized in high yield via a diazo intermediate and was protected as a bis-1,3-dioxane before substitution with various amino alcohol groups. Lanthanide macrocyclic tetra±imine complexes were obtained by a template procedure that leads to stable paramagnetic and/or ¯uorescent derivatives with anchor groups available for linkage to macromolecules.