Synthesis of New δ-(Polyfluoroalkyl)-δ-h
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Nataliya A. Tolmacheva; Igor I. Gerus; Violetta G. Dolovanyuk; Ivan S. Kondratov
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Article
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2009
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John Wiley and Sons
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English
⚖ 227 KB
## Abstract New δ‐(polyfluoroalkyl)‐δ‐hydroxy‐α‐amino acids were synthesized from the corresponding starting 3‐(benzoylamino)‐6‐(polyfluoroalkyl)‐2__H__‐pyran‐2‐ones. The key step of the synthesis was the hydrogenation of the pyrone ring. Stereoselectivity and yields depended dramatically on the re