New synthesis of oxazolidin-2-ones
โ Scribed by Marta Feroci; Achille Inesi; Vittoria Mucciante; Leucio Rossi
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 115 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Electrochemically generated tetraethylammonium peroxydicarbonate (IEAPC) and tctraethylammoniunl carbonate (TEAC) react under very mild oanditiuns, with 1,2-amiao alcohols affording, after addition of tosyl chloride, the eorrespending oxazolidin-2-ones in fair to good yields.
๐ SIMILAR VOLUMES
N-carboethoxy-N-alkyl-propargylamines react with iodine, silver tetrafluoroborate and 1-(3-dimethylaminopropyl)-3ethylcarbodiimide hydrochloride to give N-alkyl-S(E)-iodomethylidene-oxazolidin-2-ones which can be converted to the corresponding Salkynylidene-oxazolidin-2-ones by palladium chloride ca
A versatile method for the solid phase synthesis of oxazolidin-2-ones is described. A resin bound phenolic group was treated with (ยฑ)-epichlorohydrin followed by opening of the epoxide ring with sodium azide. The resulting 1-azido-3-aryloxypropan-2-ol was treated with p-nitrophenylchloroformate and
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