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New Synthesis of Derivatives of 6-Aryl-3-methyl-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine-7-carboxylic Acid

โœ Scribed by V. A. Yanchenko; V. V. Malyshev; A. M. Demchenko; M. O. Lozinskii


Book ID
111545214
Publisher
Springer US
Year
2003
Tongue
English
Weight
103 KB
Volume
39
Category
Article
ISSN
0009-3122

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Stereospecific synthesis of 6,7-dihydro-
โœ Yehia A. Ibrahim; Ahmed H. M. Elwahy; Ayman E. M. El-Fiky ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 319 KB

The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines