New synthesis of 1, 4-dihydro-1, 2, 4-triazino [3, 4-α] benzimidazoles
✍ Scribed by M. V. Povstyanoi; E. V. Logachev; P. M. Kochergin
- Book ID
- 112325165
- Publisher
- Springer US
- Year
- 1976
- Tongue
- English
- Weight
- 51 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0009-3122
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## Some 1-Substituted 3-Aryl-1,4-dihydro-1,2,4-triazino[4,3a]benzimidazoles and Their Vasodilatory Activities. -Six compounds of type (III), (V), and (VII) are tested for their vasodilatory activities. The compounds of type (III) with R 2 : hydroxyethyl, e.g. (IIId), show the best results.
UDC 547.873'785.5'735 f 724.07:543.51 2-[(8-Ethyl-, arylimino)phenethyl]-l,2,4-triazino[2,3-a]benzimidazoles were obtained by reaction of 2-aroylmethyl-l,2,4-triazino[2,3-a]benzimidazol-4H-3-ones with ethyl(aryl)amines or urea. By the action of phosphorus oxychloride, these benzimidazoles cyclize in