New syntheses of s-triazolo[1,5-a]pyridines and s-triazolo[5,1-a]isoquinoline
โ Scribed by Lin, Yang-I; Lang, S. A.
- Book ID
- 118010810
- Publisher
- American Chemical Society
- Year
- 1981
- Tongue
- English
- Weight
- 273 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The major decomposition pathway involved in the fragmentation of derivatives of the title ring systems was the loss of RCN from the five-membered ring, except when this ring had a 3-amino, 3-hydroxyl or 3-mercapto substituent. In these cases, the exocyclic substituent and at least one nitrogen atom
Nucleophilic substitution of 5-bromotriazoloisoquinoline (3) and of 7-bromo-3-methyltriazolopyridine (6) proceeds readily to give a range of 5-substituted triazoloisoquinolines (4a)-(4e), and of 7-substituted triazolopyridines (7a)-(7h) respectively. Triazoloisoquinolines have been converted into 1,