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New Structural Model of E. coli Aspartate Transcarbamylase and the Amino-acid Sequence of the Regulatory Polypeptide Chain

✍ Scribed by WEBER, KLAUS


Book ID
120437795
Publisher
Nature Publishing Group
Year
1968
Tongue
English
Weight
196 KB
Volume
218
Category
Article
ISSN
0028-0836

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A 70-amino acid zinc-binding polypeptide
✍ Bin-Bing Zhou; Grover L. Waldrop; Lawrence Lum; H. K. Schachman πŸ“‚ Article πŸ“… 2008 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 873 KB

## Abstract Interaction between a 70‐amino acid and zinc‐binding polypeptide from the regulatory chain and the catalytic (C) trimer of aspartate transcarbamoylase (ATCase) leads to dramatic changes in enzyme activity and affinity for active site ligands. The hypothesis that the complex between a C