New Strategies with Dopaminergic Drugs: Modified Formulations of Levodopa and Novel Agonists

Systematic drug receptor mapping: A new

Systematic drug receptor mapping: A new approach to the analysis of conformational energy calculations of flexible molecules with application to dopaminergic and adrenergic agonists

✍ Lilly Sanathanan; Elizabeth Danaher; Ki-Hwan Kim; Yvonne Martin 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 755 KB

The computer program PRODIS is used to find low energy conformations of flexible molecules by searching the potential energy surface(s) of one or more torsion angles via rigid rotation. The n-dimensional grid of energy versus torsion angles is then converted to a Boltzman probability distribution, w