✦ LIBER ✦

New solid-phase for automated synthesis of oligonucleotides containing an amino-alkyl linker at their 3′-end

✍ Scribed by Ulysse Asseline; Thanh Thuong Nguyen

Publisher: Elsevier Science
Year: 1990
Tongue: French
Weight: 306 KB
Volume: 31
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)94339-9

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✦ Synopsis

Immobilization of an aliphatic

amino-alcohol on a 2,2'-dithiodiethanol derivatized support via a carbamate linkage formation allows automated synthesis of oligonucleotides involving?%ino-alkyl derivatizations at their 3'-end.