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Mass spectrometry as a technique for testing the purity of drugs for biological use: The case of new antitumor cyclophosphazenes

✍ Bernard Monsarrat; Jean-Claude Promé; Jean-François Labarre; François Sournies; 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

Mass spectrometry has been used for testing the chemical purity of some new antitumor cyclophosphazene compounds. The spectrum qf N3P3Az6 (code name MYKO 63)-which exhibits noticeable activity on murine P 388, L 1210 and B 16 tumors-appeared to be remarkably simple, as most of the fragmentations aro