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New sensitive determination method of benzidine–hemoglobin adducts by gas chromatography–electron impact mass spectrometry

✍ Scribed by Ho-Sang Shin; Jin Heon Lee; Hye-Sil Ahn; Ueon-Sang Shin

Book ID
108497352
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
599 KB
Volume
783
Category
Article
ISSN
1873-376X

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✍ Ho-Sang Shin; Hye-Sil Ahn 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB

## Abstract A gas chromatography‐mass spectrometry method was developed for the determination of the propylene oxide (PO)–hemoglobin adduct. The adduct was identified as hydroxy propyl valine (HPV), and released from globin by the modified Edman degradation and extracted with ethyl ether. HPV and d