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New, Selective Catechol-O-Methyltransferase Inhibitors as Therapeutic Agents in Parkinson’s Disease

✍ Scribed by Vincenzo Bonifati; Giuseppe Meco


Book ID
114129510
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
405 KB
Volume
81
Category
Article
ISSN
0163-7258

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Catechol-O-methyltransferase inhibitors:
✍ Jasper Dingemanse 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB 👁 2 views

Substitution therapy with levodopa and a peripheral inhibitor of aromatic L-amino acid decarboxylase (AADC) is the cornerstone in the treatment of Parkinson's disease. Chronic therapy with levodopa, however, is associated with the occurrence of motor complications that are partially related to the p