## Abstract A series of 2โ(1โmethylโ3โ__n__โpropylpyrazolโ5โyl)โchromones with interesting __Phosphodiesterase__ IV inhibitition activities were synthesized. Different derivatives of the titled compounds like aminopyrimidine, thiopyrimidine, pyrazolyl were synthesized and their __Phosphodiesterase_
New routes to steroidal heterocyclic derivatives: Synthesis of biologically active pyrazolyl- and isoxazolylpregnene derivatives
โ Scribed by Abdou O. Abdelhamid; Mervat M. Abdelhalim; Gamal A. Elmegeed
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 290 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-152X
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โฆ Synopsis
Abstract
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Pyrazolylโ and isoxazolylpregnene derivatives were synthesized from the appropriate hydrazonoyl chlorides and hydroximoyl chlorides with enaminoprogesterone derivative. The newly synthesized compounds were elucidated by elemental analysis, spectral data and chemical transformation. Some products were tested towards some bacteria and some Fungalโplant pathogens
๐ SIMILAR VOLUMES
## Abstract Novel structures of bisโheterocyclic pyrrodiazole derivatives containing pyrazole were designed and synthesized. The title compounds were characterized by ^1^H NMR, IR, MS, and elemental analysis. Biological activities of three intermediate compounds and 25 pyrrodiazole derivatives were