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New regulators of melanin biosynthesis and the autodestruction of melanoma cells

✍ Scribed by Pawelek, John; Körner, Ann; Bergstrom, Alan; Bologna, Jean


Book ID
109719341
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
463 KB
Volume
286
Category
Article
ISSN
0028-0836

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## Abstract In culture, B16/C3 murine melanoma cells grown in the presence of serum undergo melanogenesis at a specific time after plating. At this time, melanin is synthesized intracellularly and then secreted into the extracellular culture fluid. We have found that melanin secretion is dependent