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New regional localisations forHAGHandPGPon human chromosome 16

✍ Scribed by J. C. Mulley; D. F. Callen

Book ID
104701793
Publisher
Springer
Year
1986
Tongue
English
Weight
290 KB
Volume
74
Category
Article
ISSN
0340-6717

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✦ Synopsis

The chromosomal locations for the electrophoretic markers hydroxyacyl glutathione hydrolase (HAGH) and phosphoglycolate phosphatase (PGP) were examined using a human-mouse hybrid panel of chromosome 16. The assignment for HAGH was confirmed to chromosome 16 using a cell line with chromosome 16 as the only human chromosome. Both HAGH and PGP were present only in cell lines containing human 16p13. This localisation for PGP indirectly places the tightly linked genes for the alpha-globin cluster and adult polycystic kidney disease on 16p13.

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