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New quantification method for estradiol in the prostatic tissues of benign prostatic hyperplasia using liquid chromatography–tandem mass spectrometry

✍ Scribed by Seiji Arai; Yoshimichi Miyashiro; Yasuhiro Shibata; Bunzo Kashiwagi; Yukio Tomaru; Mikio Kobayashi; Yoko Watanabe; Seijiro Honma; Kazuhiro Suzuki

Book ID
116892385
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
485 KB
Volume
75
Category
Article
ISSN
0039-128X

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## Abstract A sensitive high‐performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of quetiapine in rat plasma. Following liquid–liquid extraction, the analyte was separated using a gradient mobile phase on a reverse‐phase column and an