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New protein kinase C activator regulates amyloid precursor protein processing in vitro by increasing α-secretase activity

✍ Scribed by Hong-Qi Yang; Jing Pan; Mao-Wen Ba; Zhi-Kun Sun; Guo-Zhao Ma; Guo-Qiang Lu; Qin Xiao; Sheng-Di Chen


Book ID
109026039
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
832 KB
Volume
26
Category
Article
ISSN
0953-816X

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## Abstract All‐trans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (