New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2). Identification and synthesis of N-propyl-5-substituted isoquinolones
✍ Scribed by Trabanco, Andrés A. ;Duvey, Guillaume ;Cid, José María ;Macdonald, Gregor J. ;Cluzeau, Philippe ;Nhem, Vanthea ;Furnari, Rocco ;Behaj, Nadia ;Poulain, Géraldine ;Finn, Terry ;Poli, Sonia ;Lavreysen, Hilde ;Raux, Alexandre ;Thollon, Yves ;Poirier, Nicolas ;D'Addona, David ;Andrés, José Ignacio ;Lutjens, Robert ;Le Poul, Emmanuel ;Imogai, Hassan ;Rocher, Jean-Philippe
- Book ID
- 118220281
- Publisher
- The Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 213 KB
- Volume
- 2
- Category
- Article
- ISSN
- 2040-2503
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Based on SAR in the alkyne class of mGlu5 receptor negative allosteric modulators and a set of amidebased positive allosteric modulators, optimized substitution of the aryl 'b' ring was used to create substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides. Results from an mGlu5 receptor functional a
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v