𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2). Identification and synthesis of N-propyl-5-substituted isoquinolones

✍ Scribed by Trabanco, Andrés A. ;Duvey, Guillaume ;Cid, José María ;Macdonald, Gregor J. ;Cluzeau, Philippe ;Nhem, Vanthea ;Furnari, Rocco ;Behaj, Nadia ;Poulain, Géraldine ;Finn, Terry ;Poli, Sonia ;Lavreysen, Hilde ;Raux, Alexandre ;Thollon, Yves ;Poirier, Nicolas ;D'Addona, David ;Andrés, José Ignacio ;Lutjens, Robert ;Le Poul, Emmanuel ;Imogai, Hassan ;Rocher, Jean-Philippe


Book ID
118220281
Publisher
The Royal Society of Chemistry
Year
2011
Tongue
English
Weight
213 KB
Volume
2
Category
Article
ISSN
2040-2503

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Design and synthesis of substituted N-(1
✍ Mu-Fa Zou; Jianjing Cao; Alice L. Rodriguez; P. Jeffrey Conn; Amy Hauck Newman 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 510 KB

Based on SAR in the alkyne class of mGlu5 receptor negative allosteric modulators and a set of amidebased positive allosteric modulators, optimized substitution of the aryl 'b' ring was used to create substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides. Results from an mGlu5 receptor functional a

ChemInform Abstract: Synthesis and SAR o
✍ Richard Williams; Kari A. Johnson; Patrick R. Gentry; Colleen M. Niswender; Char 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 16 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v