✦ LIBER ✦
New plot showing the existence of cooperativity, anticooperativity, and an arbitrary value of the neighbor-exclusion parameter in systems of ligand binding to linear biopolymers
✍ Scribed by Takashi Tsuchiya
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1983
- Tongue
- English
- Weight
- 503 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0006-3525
No coin nor oath required. For personal study only.
✦ Synopsis
Synopsis
A new way of plotting the isotherm for ligand binding to linear biopolymers is presented.
In this plot the isotherm for noncooperative binding of ligands of length n (n-mers) becomes a straight line and the existence of cooperativity and anticooperativity between bound ligands is detected by appearance of opposite convexity of the curved isotherm. It is also usable for cases of fractional n values. Usefulness of the new plot in determining precise mechanisms of binding is shown using experimental data.