New phenanthrenes from Trigonostemon lii Y.T. Chang

✍ Scribed by Xu-Jia Hu; Yue-Hu Wang; Ling-Yi Kong; Hong-Ping He; Suo Gao; Hai-Yang Liu; Jian Ding; Hua Xie; Ying-Tong Di; Xiao-Jiang Hao

• Book ID: 104096493
• Publisher: Elsevier Science
• Year: 2009
• Tongue: French
• Weight: 405 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2009.03.186

✦ Synopsis

Three new phenanthrenes, thrigonosomone A (1), 6,9-O-dedimethyltrigonostemone (2), and thrigonosomone B (3) were isolated from Trigonostemon lii. Their structures were elucidated by spectroscopic methods. Thrigonosomone A (1) possessed a novel seven-membered cyclic anhydride moiety, and its relative configuration was determined by chemical computation and ROESY experiment. The cytotoxicity of compounds 1-3 was also evaluated.