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New perspectives on the assembly process of mitochondrial respiratory chain complex cytochrome c oxidase

✍ Scribed by Cristina Ugalde; Marieke J.H Coenen; Murtada H Farhoud; Stefanie Gilinsky; Werner J.H Koopman; Lambert P van den Heuvel; Jan A.M Smeitink; Leo G.J Nijtmans

Book ID
117798462
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
349 KB
Volume
2
Category
Article
ISSN
1567-7249

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## Abstract Brain mitochondrial cytochrome oxidase and respiratory activities were compared after __in vivo__ and __in vitro__ exposure to cyanide. For the __in vivo__ studies, mice were exposed to a non‐lethal (4 mg kg^βˆ’1^) or lethal (20 mg kg^βˆ’1^) dose of KCN. From these mice, purified brain mito