New Pentacyclic Cucurbitane Glucosides from the Fruits of Citrullus colocynthisSchrad.

✍ Scribed by Durey Nayab; Shagufta Perveen; Zaheer Ahmed; Abdul Malik

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: German
• Weight: 164 KB
• Volume: 93
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200900341

✦ Synopsis

Abstract

Colocynthins A–C (1–3, resp.), new pentacyclic cucurbitane type triterpene glucosides, have been isolated from the AcOEt‐soluble fraction of the fruits of Citrullus colocynthis, along with three known compounds, β‐sitosterol 3‐O‐β‐D‐glucopyranoside, elaterinide, and bryoamaride. Their structures were determined on the basis of ^1^H‐ and ^13^C‐NMR spectra, DEPT, and COSY, NOESY, HMQC, and HMBC experiments.