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New pathways of trichloroethylene metabolism

✍ Scribed by Dekant, W.; Henschler, D.

Book ID: 123409971
Publisher: Elsevier Science
Year: 1983
Tongue: English
Weight: 111 KB
Volume: 18
Category: Article
ISSN: 0378-4274
DOI: 10.1016/0378-4274(83)90521-0

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Volunteers inhaled a constant concentration of 50 ppm trichloroethylene (Tri) for 6 hrs per day on 5 consecutive days. Simultaneous ethanol (EtOH) ingestion (blood level 0.6%) inhibits the metabolization of Tri to trichloroethanol (TCE) and trichloroacetic acid (TCA) by 40% on the average. Oxidation