New Partners for HP1 in Transcriptional Gene Silencing
โ Scribed by Paul D. Kaufman
- Book ID
- 116754985
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 64 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1097-2765
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## Abstract Heterochromatin protein 1 (HP1) is a positive regulator of active transcription in euchromatin. HP1 was first identified in __Drosophila melanogaster__ as a major component of heterochromatin. Most eukaryotes have at least three isoforms of HP1, which are conserved in overall structure
## Abstract The human intestinal pathogen __Entamoeba histolytica__ has a number of virulence factors which can cause damage to the host. Transcriptional silencing of the gene coding for one of its major toxic molecules, the amoebapore (__Ehapโa__), occurred following the transfection of amoebic tr