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New opportunities in anti-hepatitis C virus drug discovery: Targeting NS4B

✍ Scribed by Roopa Rai; Jerome Deval

Book ID
113458487
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
336 KB
Volume
90
Category
Article
ISSN
0166-3542

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## Abstract Many viruses can inhibit protein synthesis in their host cells by targeting translation (β€œtranslational shutoff”). There are few reports on the effects of hepatitis C virus (HCV) infection on protein synthesis, because of the lack of a reproducible tissue culture system for HCV. In this