𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New "ofloxacin" type antibacterial agents. Incorporation of the spiro cyclopropyl group at N-1

✍ Scribed by Kiely, John S.; Schroeder, Mel C.; Sesnie, Josephine C.

Book ID
127284031
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
647 KB
Volume
31
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis, pharmacokinetics, and biologi
Synthesis, pharmacokinetics, and biological activity of a series of new pyridonecarboxylic acid antibacterial agents bearing a 5-fluoro-2-pyridyl group or a 3-fluoro-4-pyridyl group at N-1
✍ Sung June Yoon; Yong Ho Chung; Chi Woo Lee; Yoon Seok Oh; Dong Rack Choi; Nam Do 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 490 KB

## Abstract The 1‐(5‐fluoro‐2‐pyridyl) or 1‐(3‐fluoro‐4‐pyridyl) group was introduced in the syntheses of new pyridonecarboxylic acid antibacterial agents. 1‐(5‐Fluoro‐2‐pyridyl)‐6‐fluoro‐1,4‐dihydro‐7‐(4‐methyl‐1‐piperazinyl)‐4‐oxoquinolone‐3‐carboxylic acid 7b (DW‐116) showed a moderate __in vitr

ChemInform Abstract: Synthesis, Pharmaco
ChemInform Abstract: Synthesis, Pharmacokinetics, and Biological Activity of a Series of New Pyridonecarboxylic Acid Antibacterial Agents Bearing a 5-Fluoro-2- pyridyl Group or a 3-Fluoro-4-pyridyl Group at N-1.
✍ S. J. YOON; Y. H. CHUNG; C. W. LEE; Y. S. OH; D. R. CHOI; N. D. KIM; J. K. LIM; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Synthesis, Pharmacokinetics, and Biological Activity of a Series of New Pyridonecarboxylic Acid Antibacterial Agents Bearing a 5-Fluoro-2-pyridyl Group or a 3-Fluoro-4-pyridyl Group at N-1. -A variety of new quinolones bearing fluorinated pyridyl groups at N1 ( cf. (VIII), (IX); 18 examples) are syn