Discovery of cytochrome P450 1B1 inhibit
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Young-Jin Chun; Sanghee Kim
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Article
📅
2003
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John Wiley and Sons
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English
⚖ 155 KB
## Abstract Human cytochrome P450 (CYP)1B1 is a major enzyme for carcinogenic estrogen metabolism and involved in the metabolic activation of procarcinogens of the polycyclic aromatic hydrocarbons (PAHs). CYP1B1 is known to be expressed at a high frequency in various human cancers, but not in norma