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New methods for β-conjugate addition and β-hydroxyalkylation of enones

✍ Scribed by Sunggak Kim; Phil Ho Lee

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
223 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis

S-Conjugate addition and 5-hydroxyalkylation of enones have been accomplished by the reaction of ylides, derivated from enones via phosphoniosilylation, with activated olefins and aldehydes in the presence of trimethylsilyl triflate in tetrahydrofuran at -78 OC and subsequent elimination of phosphonium salts by one-pot procedure.

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