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New method for the synthesis of 8-azasteroids: Synthesis of benzo[a]cyclohexa[f]furo[2,3-g]-quinolizines from 2-cinnamoylcyclohexa[b]oxirane

✍ Scribed by G. V. Pshenichnyi


Book ID
105102346
Publisher
Springer US
Year
1994
Tongue
English
Weight
269 KB
Volume
30
Category
Article
ISSN
0009-3122

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A new synthesis of the 2-dimethylamino-4-hydroxy-6-methoxymethyl-3H-imidazo [4', 5' :3,4] pyfido[2,3-b]indole, used as key intermediate in the total synthesis of the alkaloids grossularines -1 and -2. based on the step-wise formation of the pyfidine and imidazole tings, is described.