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New method for the synthesis of 1-aminospiro[2.2]pentane-1,4-dicarboxylic acid

✍ Scribed by Chemagin, A. V.; Yashin, N. V.; Averina, E. B.; Kuznetsova, T. S.; Zefirov, N. S.


Book ID
110160071
Publisher
Springer
Year
2008
Tongue
English
Weight
129 KB
Volume
419
Category
Article
ISSN
0012-5008

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## Abstract A process for double deuterium labeling of an alcohol was developed. The process was utilized in the subsequent tritium labeling of a secondary alcohol with high specific activity (24 Ci/mmol) by reduction of the corresponding ketone using sodium borotritide. The starting ketone was fir