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New method for the synthesis of 1-aminoalkyl-phosphonic and phosphinic acids Communication 4. Synthesis of (1-aminoalkyl)phenylphosphinic acids

✍ Scribed by M. I. Kabachnik; T. Ya. Medved


Book ID
112490616
Publisher
Springer
Year
1955
Tongue
English
Weight
613 KB
Volume
3
Category
Article
ISSN
1573-9171

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A new convenient route for the synthesis
✍ Roeland C. Vollinga; Wiro M. P. B. Menge; Hendrik Timmerman 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 293 KB

## Abstract A new route for the synthesis of 4(5)‐(ω‐aminoalkyl)‐1 __H__‐imidazoles 1 on a preparative scale through C5 lithiation of a 1,2‐diprotected imidazole is described. When the described 1,2‐diprotected 5‐lithio‐imidazole is treated with a 1‐chloro‐ω‐iodoalkane 5, selective substitution of