New Isoflavone C-Glycosides from Pueraria lobata

✍ Scribed by Guo-Hui Li; Qing-Wen Zhang; Lei Wang; Xiao-Qi Zhang; Wei-Cai Ye; Yi-Tao Wang

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: German
• Weight: 165 KB
• Volume: 94
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.201000205

✦ Synopsis

Abstract

Three new isoflavone C‐glycosides, along with two known isoflavone O‐glycosides, were isolated from the roots of Pueraria lobata (Willd.) Ohwi. The structures of the new compounds were elucidated as 4′,7‐dihydroxy‐3′‐methoxyisoflavone 8‐C‐[β‐d‐glucopyranosyl‐(1→6)]‐β‐d‐glucopyranoside (1), 4′,7‐dihydroxy‐3′‐methoxyisoflavone 8‐C‐[β‐d‐apiofuranosyl‐(1→6)]‐β‐d‐glucopyranoside (2), and 8‐C‐β‐d‐glucopyranosyl‐4′,7‐dihydroxy‐3′‐methoxyisoflavone 4′‐O‐β‐d‐glucopyranoside (3) on the basis of spectroscopic methods, especially 2D‐NMR and MS analyses. The known compounds isolated were identified by comparison of their physical and spectroscopic data with those reported in the literature.