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New insights into the subversion of the chemokine system by poxviruses

✍ Scribed by Antonio Alcami


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
160 KB
Volume
37
Category
Article
ISSN
0014-2980

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✦ Synopsis


Abstract

Viruses encode immune evasion mechanisms to survive in the immunocompetent host. Chemokines mediate the migration of immune cells and their critical role in immunity is emphasized by the numerous virus‐encoded strategies to modulate their activity. Evidence published in this issue of the European Journal of Immunology uncovers novel mechanisms encoded by vaccinia virus to inhibit the chemokine‐mediated migration of DC, an important event in the initiation of the immune response to viral infections.

See accompanying article: http://dx.doi.org/10.1002/eji.200636230


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