New insights into the subversion of the chemokine system by poxviruses
β Scribed by Antonio Alcami
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 160 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0014-2980
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β¦ Synopsis
Abstract
Viruses encode immune evasion mechanisms to survive in the immunocompetent host. Chemokines mediate the migration of immune cells and their critical role in immunity is emphasized by the numerous virusβencoded strategies to modulate their activity. Evidence published in this issue of the European Journal of Immunology uncovers novel mechanisms encoded by vaccinia virus to inhibit the chemokineβmediated migration of DC, an important event in the initiation of the immune response to viral infections.
See accompanying article: http://dx.doi.org/10.1002/eji.200636230
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