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New insights into the role of PML in tumour suppression

โœ Scribed by Salomoni, P; Ferguson, BJ; Wyllie, AH; Rich, T


Book ID
109846907
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
811 KB
Volume
18
Category
Article
ISSN
0007-0610

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The genes TSC1 and TSC2, encoding hamartin and tuberin, respectively, have been shown to be involved in the development of the autosomal dominantly inherited tumor syndrome tuberous sclerosis (TSC). However, inactivation of these genes has also been demonstrated to be associated with sporadic bladde