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New insights into the pathogenesis of systemic lupus erythematosus

✍ Scribed by Vasileios C. Kyttaris; Christina G. Katsiari; Yuang-Taung Juang; George C. Tsokos

Book ID
107553798
Publisher
Springer
Year
2005
Tongue
English
Weight
475 KB
Volume
7
Category
Article
ISSN
1523-3774

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New insights into disease pathogenesis from mouse lupus genetics
✍ Trine N JΓΈrgensen; Melanie R Gubbels; Brian L Kotzin πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 133 KB

Full manifestation of mouse lupus, similar to the human disease in its severe form, is characterized by elevated antinuclear autoantibody levels and the development of kidney disease. Considerable evidence supports a genetic basis for lupus. The functional dissection of susceptibility loci in multig