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New insights into the functional role of the rheumatoid arthritis shared epitope

✍ Scribed by Denise E. de Almeida; Song Ling; Joseph Holoshitz

Book ID
113622477
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
771 KB
Volume
585
Category
Article
ISSN
0014-5793

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πŸ“œ SIMILAR VOLUMES

Activation of nitric oxide signaling by
Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope
✍ Song Ling; Angela Lai; Olga Borschukova; Paul Pumpens; Joseph Holoshitz πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 388 KB

## Abstract ## Objective Susceptibility to rheumatoid arthritis (RA) is closely associated with __HLA–DRB1__ alleles encoding a shared epitope (SE) in positions 70–74 of the HLA–DRΞ² chain. The mechanistic basis for this association is unknown. Given the proposed pathogenic role of nitric oxide (NO