New insights into p53 protein stabilisation in oral squamous cell carcinoma
β Scribed by M Partridge; S Kiguwa; G Emilion; S Pateromichelakis; R A'Hern; J.D Langdon
- Book ID
- 114394264
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 314 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1368-8375
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π SIMILAR VOLUMES
To examine the expression of p53 protein and gene alterations in oral epithelial lesions including epithelial dysplasias and primary squamous cell carcinomas, immunohistochemical and temperature gradient gel electrophoresis (TGGE) methods were applied to formalin-fixed and paraffin-embedded tissues.
## Background: The objective of the study was to evaluate the pathogenetic and prognostic value of p53 protein expression in squamous cell carcinoma of the vulva. ## Methods: The clinical data in charts of 167 patients with international federation of gynecology and obstetrics (figo) stages i-iii