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New Insights into Mechanisms of γ-Diketone-Induced Axonopathy

✍ Scribed by Desire Tshala-Katumbay; Paul Desjardins; Mohammad Sabri; Roger Butterworth; Peter Spencer


Book ID
106484413
Publisher
Springer
Year
2009
Tongue
English
Weight
327 KB
Volume
34
Category
Article
ISSN
0364-3190

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## Abstract The biologically active metabolite of vitamin D, 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by stereospecific interaction of 1,25(OH)~2~D~3~ with the vitamin D receptor (VDR