New inclusion body in a rat renal cell

✍ Scribed by Chapman, George B. ;Sheikh, Shehzad M.

• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 462 KB
• Volume: 241
• Category: Article
• ISSN: 0003-276X
• DOI: 10.1002/ar.1092410103

✦ Synopsis

Background and Methods: In an effort to review ultrastructural features of cells in the kidney of a male rat, transmission electron microscopy was used to study ultrathin sections.

Results: One light cell in a collecting tubule contained a 2.3-pm long linear array of electron-dense asymmetric structures in a granular zone of greater electron density than the general cytoplasm. This inclusion body could be interpreted to consist of a parallel array of 100-150-nm x 24-nm electron-dense rodlets, or a parallel array of 100-150-nm x 67-nm tubules. The inclusion showed no association with any cell organelle. The origin, chemical nature, frequency of occurrence, and functional significance of this inclusion are unknown.

ConcZusions: Although this inclusion body somewhat resembles previously described inclusions or granules, the differences in dimensions, frequency, and relation to other cell structures suggest it is a new observation.