New Hydrazine-Based Organocatalyst for Asymmetric Diels-Alder Reaction of 1,2-Dihydropyridines
β Scribed by Takeshita, Mitsuhiro; Okuyama, Yuko; Osone, Kenichi; Nakano, Hiroto
- Book ID
- 118270699
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 2012
- Tongue
- English
- Weight
- 907 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0385-5414
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π SIMILAR VOLUMES
A new class of C 2 -symmetric 3,3 0 -dialkoxy-2,2 0 -bipyrrolidines have been designed and developed for asymmetric organocatalytic Diels-Alder reactions of a,b-unsaturated aldehydes. The bipyrrolidines combined with HClO 4 were found to be effective organocatalysts for enantioselective Diels-Alder
Diketopiperazines have been utilized as chiral auxiliaries for asymetric Diels-Alder reactions. Cyclo-Sphenylalanyl-R-proline (2) was found to be the most promising of these auxiliaries and afforded Diels-Alder adducts in high chemical yield (78 -95%), with endo selectivities generally greater than