New human cervical carcinoma cell lines with integrated HPV16
β Scribed by Sarah Money; X Han; DLS Eustace; RJ Jewers; Belinda Dagg; Eadie Heyderman
- Book ID
- 119157585
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 150 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0277-5379
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A total of 12 carcinoma cell lines of the human uterine cervix were established from 5 keratinizing and 5 nonkeratinizing squamous-cell carcinomas, and 2 small-cell carcinomas. Of these, 10 lines grew as adherent cells and 2 as floating aggregates. All lines showed (i) similarity in morphology to th
A total of six cervical carcinoma cell lines, of which two contained human papillomavirus (HPV) type 16 and four contained HPV type 18 DNA, were examined for viral RNA expression by spot-blot hybridization. All six cell lines contained HPV-specific cytoplasmic poly(A)-containing RNA. The same RNA sp