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New host factors and pathways involved in CD4 downregulation in HIV-1 infected cells

โœ Scribed by Landi, Alessia; Vermeire, Jolien; Iannucci, Veronica; Vanderstraeten, Hanne; Naessens, Evelien; Bentahir, Mostafa; Verhasselt, Bruno


Book ID
121621871
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
67 KB
Volume
10
Category
Article
ISSN
1742-4690

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## Abstract The CD27^โˆ’^ (naive) B cells of HIVโ€1 infected patients have been shown to be increased in frequency and to be activated, as indicated by high CD38 expression on the cell surface. CXCR5, a B cell chemokine receptor, is expressed on circulating CD27^โˆ’^ (naive) B cells and plays a pivotal