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New fungal metabolite geranylgeranyltransferase inhibitors with antifungal activity

✍ Scribed by Singh, Sheo B.; Kelly, Rosemarie; Guan, Ziqiang; Polishook, Jon D.; Dombrowski, Anne W.; Collado, Javier; González, Antonio; Pelaez, Fernando; Register, Elizabeth; Kelly, Theresa M.; Bonfiglio, Cynthia; Williamson, Joanne M.


Book ID
120940597
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
152 KB
Volume
19
Category
Article
ISSN
1478-6419

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Diepoxins (l-4) , unique, spiroketal-linked bisepoxides have been isolated from a filamentous fungus. Structures were assigned to these compounds primarily on the basis of NMR data.