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New functions for the matrix metalloproteinases in cancer progression

✍ Scribed by Egeblad, Mikala; Werb, Zena

Book ID
109948945
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
394 KB
Volume
2
Category
Article
ISSN
1474-1776

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Basic cancer research has mainly focused on mutations in cancer cells that result in either gain-of-function in oncogenes or loss-of-function in tumour-suppressor genes 1 . However, the EXTRACELLULAR MATRIX (ECM) of tumours and the non-cancerous, stromal cells within tumours also have an important i

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studies on MMP-2 in PCa patients, we question the usefulness of pro-MMP-2 measurements in blood as a suitable predictor of the progression of prostate cancer. Sincerely yours,