The renal clearance of melphalan and the fraction unbound in plasma were determined after intravenous infusion of 5 mg/m2 over 5 min in nine patients with cancer to obtain information regarding the mechanism of renal handling of melphalan. Four of the patients underwent bone marrow transplantation a
New formulation intravenous melphalan in the treatment of patients with metastitic renal cancer
โ Scribed by Carla I. Falkson
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 84 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Pharmacokinetic studies in 11 patients with multiple myeloma were undertaken on the first and last days of one course of chemotherapy. The drug was administered PO in single doses of 6-14 mg daily. Melphalan concentrations were determined by high-performance liquid chromatography. The interpatient v
## Abstract A new formulation of a sublingual tablet with 10 mg apomorphine was examined in 13 patients with Parkinson's disease. Vitamin C (250 mg) was added sublingually to lower the salivary pH. Four patients received sublingual apomorphine and nine received sublingual apomorphine as well as vit