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New Flavanones from the Leaves of Cryptocarya chinensis and Their Antituberculosis Activity

✍ Scribed by Tsung-Hsien Chou; Jih-Jung Chen; Chien-Fang Peng; Ming-Jen Cheng; Ih-Sheng Chen


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
362 KB
Volume
8
Category
Article
ISSN
1612-1872

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✦ Synopsis


Abstract

Four new flavanones, cryptoflavanones A–D (1–4, resp.), together with eight known compounds, were isolated from the leaves of Cryptocarya chinensis. The structures of these new compounds were determined by spectral analyses. Among the isolated compounds, pinocembrin (5) and cryptocaryone (6) exhibited antituberculosis activity against Mycobacterium tuberculosis H~37~Rv strain in vitro with MIC values of 3.5 and 25.0β€…ΞΌg/ml, respectively.


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