Preparation of nitriles from carboxylic
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Vincent J. Huber; Richard A. Bartsch
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Article
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1998
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Elsevier Science
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French
โ 435 KB
Reaction of 2,4-dinitrobenzenesulfonamide with acyl chlorides in the presence of excess triethylamine produces the corresponding nitrile in good to fair yields. Mechanistic studies indicate that the reaction proceeds via a Smiles rearrangement of the initially formed N-(2,4dinitrohenzenesulfonyl)ami